HitPredict

Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 464 Hs			1 840
+	Hs
		320788 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		346071 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		379670 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		320784 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		347469 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		320861 USF2_HUMAN (199-463): 9.99e-26: 109: 17.34		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		378955 MYCN_HUMAN (1-464): 1.72e-89: 282: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		345782 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		346070 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		345856 MYC_HUMAN (7-463): 5.91e-69: 228: 34.16		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		503745 SC24C_HUMAN (17-348): 1.44e-32: 133: 16.29		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92