Protein: IGHG3
Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region)

Gene: IGHG3
Organism: Homo sapiens
Interactions: 42
UniProt ID: P01860

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0003823 - antigen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

379425

CAH8
Carbonic anhydrase-related protein

2

4

High-throughput

0.637

High

132966

MATN2
Matrilin-2

1

9

High-throughput

0.575

High

210649

KLK10
Kallikrein-10

1

14

High-throughput

0.575

High

379174

IGHG1
Immunoglobulin heavy constant gamma 1

1

17

High-throughput

0.575

High

379326

IGHG2
Immunoglobulin heavy constant gamma 2

1

17

High-throughput

0.575

High

379416

HV431
Immunoglobulin heavy variable 4-31

1

20

High-throughput

0.575

High

379422

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

2

High-throughput

0.575

High

379415

ALDH2
Aldehyde dehydrogenase, mitochondrial

2

4

High-throughput

0.552

High

379423

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

2

9

High-throughput

0.552

High

379440

SNX27
Sorting nexin-27

2

9

High-throughput

0.504

High

194439

P2RX6
P2X purinoceptor 6

1

5

High-throughput

0.445

High

254717

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.445

High

379417

BIP
Endoplasmic reticulum chaperone BiP

1

14

High-throughput

0.445

High

379419

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

379420

AATC
Aspartate aminotransferase, cytoplasmic

1

6

High-throughput

0.445

High

379424

CCR1
C-C chemokine receptor type 1

1

13

High-throughput

0.445

High

379427

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

379430

CRDL2
Chordin-like protein 2

1

4

High-throughput

0.445

High

379434

OR2LD
Olfactory receptor 2L13

1

1

High-throughput

0.445

High

379437

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

7

High-throughput

0.445

High

379444

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

8

High-throughput

0.445

High

379447

NEMO
NF-kappa-B essential modulator

1

7

High-throughput

0.437

High

379421

S10A4
Protein S100-A4

1

0

High-throughput

0.426

High

325255

OR2A4
Olfactory receptor 2A4

1

7

High-throughput

0.407

High

335217

CXB5
Gap junction beta-5 protein

1

6

High-throughput

0.407

High

379418

ADT3
ADP/ATP translocase 3

1

9

High-throughput

0.407

High

379426

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

8

High-throughput

0.407

High

379428

CR021
UPF0711 protein C18orf21

1

7

High-throughput

0.407

High

379429

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

9

High-throughput

0.407

High

379431

CIR1
Corepressor interacting with RBPJ 1

1

7

High-throughput

0.407

High

379432

CERS3
Ceramide synthase 3

1

7

High-throughput

0.407

High

379433

NRSN1
Neurensin-1

1

6

High-throughput

0.407

High

379435

RHBL4
Rhomboid-related protein 4

1

7

High-throughput

0.407

High

379436

PIGT
GPI-anchor transamidase component PIGT

1

6

High-throughput

0.407

High

379438

R51A1
RAD51-associated protein 1

1

1

High-throughput

0.407

High

379441

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

11

High-throughput

0.407

High

379442

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

8

High-throughput

0.407

High

379443

PHF11
PHD finger protein 11

1

11

High-throughput

0.407

High

379445

RN115
E3 ubiquitin-protein ligase RNF115

1

8

High-throughput

0.407

High

331618

MBD4
Methyl-CpG-binding domain protein 4

1

0

High-throughput

0.232

Low

379439

SKA1
SKA complex subunit 1

1

0

High-throughput

0.232

Low

379446

FHOD1
FH1/FH2 domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025