Interactor 1: MYCN (P04198)
N-myc proto-oncogene protein (Class E basic helix-loop-helix protein 37) (bHLHe37)
Gene: MYCN

Interactor 2: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 29028833, 10229200, 20946988, 18488021, 1935896, 24859015, 26062444, 25175806, 2006410, 35013218, 17289033, 18003922, 27728805, 23792191, 10597290
Identification Methods affinity chromatography technology, pull down, biochemical, protein complementation assay, anti bait coimmunoprecipitation, two hybrid, beta galactosidase complementation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 6 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 464
Hs

1 160
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Rn
+ Hs
+ Hs
+ Gg
+ Hs
+ At
+ At
+ At
+ At
+ At
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024