HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	15324660
Identification Methods	affinity chromatography technology, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 644 Hs			1 245
+	Hs
		409044 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		409008 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		409047 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		409014 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		927293 K2C78_HUMAN (119-543): 1.51e-130: 395: 55.09		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		409015 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		409055 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		409042 K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		982264 K2C78_HUMAN (119-543): 1.51e-130: 395: 55.09		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		380460 K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Mm
		910243 K22O_MOUSE (1-605): 7.45e-75: 252: 55.26		1433E_MOUSE (2-243): 1.31e-144: 406: 63.53
+	Hs
		909746 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		927229 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683500 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		380568 K2C1_HUMAN (1-511): 2.63e-77: 260: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		904437 KRT85_HUMAN (69-552): 3.19e-81: 267: 44.88		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		905163 KRT82_HUMAN (61-575): 4.79e-77: 256: 44.85		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		684163 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		982214 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		904786 K2C1B_HUMAN (62-511): 4.84e-63: 220: 64.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33