Protein: DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain (DP(W3)) (DP(W4)) (HLA-SB alpha chain) (MHC class II DP3-alpha) (MHC class II DPA1)

Gene: DPA1, HLA-DPA1
Organism: Homo sapiens
Interactions: 121
UniProt ID: P20036

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0002250 - adaptive immune response
GO:0002503 - peptide antigen assembly with MHC class II protein complex
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

133168

QSOX1
Sulfhydryl oxidase 1

3

5

High-throughput

0.861

High

409558

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

3

18

High-throughput

0.861

High

627502

ERBB3
Receptor tyrosine-protein kinase erbB-3

3

20

High-throughput

0.861

High

627509

SPB4
Serpin B4

3

1

High-throughput

0.861

High

627523

PTPRS
Receptor-type tyrosine-protein phosphatase S

3

1

High-throughput

0.861

High

627538

QSOX2
Sulfhydryl oxidase 2

3

5

High-throughput

0.861

High

627539

BT2A1
Butyrophilin subfamily 2 member A1

3

11

High-throughput

0.861

High

627551

SORL
Sortilin-related receptor

3

3

High-throughput

0.861

High

627566

ULBP3
UL16-binding protein 3

3

19

High-throughput

0.861

High

627569

RN167
E3 ubiquitin-protein ligase RNF167

2

8

High-throughput

0.811

High

409258

HLAA
HLA class I histocompatibility antigen, A alpha chain

2

20

High-throughput

0.789

High

627535

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

20

High-throughput

0.789

High

627557

KIRR1
Kin of IRRE-like protein 1

2

4

High-throughput

0.789

High

627582

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

2

4

High-throughput

0.789

High

62096

KLRG2
Killer cell lectin-like receptor subfamily G member 2

3

20

High-throughput

0.770

High

62904

POTEF
POTE ankyrin domain family member F

2

1

High-throughput

0.726

High

627521

SRBP2
Sterol regulatory element-binding protein 2

4

3

High-throughput

0.694

High

380612

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

19

High-throughput

0.691

High

438868

CD1A
T-cell surface glycoprotein CD1a

1

20

High-throughput

0.691

High

627516

DRB3
HLA class II histocompatibility antigen, DR beta 3 chain

1

19

High-throughput

0.691

High

627545

FGRL1
Fibroblast growth factor receptor-like 1

1

5

High-throughput

0.691

High

136478

GOLI4
Golgi integral membrane protein 4

3

1

High-throughput

0.667

High

212055

B4GT5
Beta-1,4-galactosyltransferase 5

3

3

High-throughput

0.667

High

251069

B4GT3
Beta-1,4-galactosyltransferase 3

3

3

High-throughput

0.667

High

251142

B4GT4
Beta-1,4-galactosyltransferase 4

3

3

High-throughput

0.667

High

270131

FKTN
Ribitol-5-phosphate transferase FKTN

3

1

High-throughput

0.667

High

627503

FUT4
Alpha-(1,3)-fucosyltransferase 4

3

2

High-throughput

0.667

High

627507

TNFL9
Tumor necrosis factor ligand superfamily member 9

3

2

High-throughput

0.667

High

627517

EFNB1
Ephrin-B1

3

3

High-throughput

0.667

High

627530

EFNB3
Ephrin-B3

3

3

High-throughput

0.667

High

627542

CHSS1
Chondroitin sulfate synthase 1

3

5

High-throughput

0.667

High

627547

DCBD1
Discoidin, CUB and LCCL domain-containing protein 1

3

8

High-throughput

0.667

High

627548

GLT11
Polypeptide N-acetylgalactosaminyltransferase 11

3

10

High-throughput

0.667

High

627549

TIP
T-cell immunomodulatory protein

3

4

High-throughput

0.667

High

627552

S67A1
Solute carrier family 67 member A1

3

9

High-throughput

0.667

High

627577

AT132
Polyamine-transporting ATPase 13A2

3

15

High-throughput

0.667

High

627584

LCAP
Leucyl-cystinyl aminopeptidase

3

10

High-throughput

0.667

High

627585

DSE
Dermatan-sulfate epimerase

3

2

High-throughput

0.667

High

627590

HS3SB
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

3

1

High-throughput

0.667

High

627586

KDIS
Kinase D-interacting substrate of 220 kDa

2

0

High-throughput

0.660

High

387373

APOE
Apolipoprotein E

3

0

High-throughput

0.638

High

533587

CLUS
Clusterin

3

0

High-throughput

0.638

High

627526

DAG1
Dystroglycan 1

3

0

High-throughput

0.638

High

627571

FKRP
Ribitol 5-phosphate transferase FKRP

3

0

High-throughput

0.638

High

627572

S38AA
Solute carrier family 38 member 10

4

5

High-throughput

0.630

High

407033

HG2A
HLA class II histocompatibility antigen gamma chain

1

9

Small-scale

0.618

High

627505

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

18

High-throughput

0.618

High

627512

EPHA4
Ephrin type-A receptor 4

1

15

High-throughput

0.618

High

627529

EPHA7
Ephrin type-A receptor 7

1

10

High-throughput

0.618

High

627540

PCAT2
Lysophosphatidylcholine acyltransferase 2

2

4

High-throughput

0.611

High

627550

SCRB1
Scavenger receptor class B member 1

2

4

High-throughput

0.611

High

627576

CHSTB
Carbohydrate sulfotransferase 11

2

10

High-throughput

0.611

High

627583

EGFL7
Epidermal growth factor-like protein 7

2

3

High-throughput

0.611

High

60815

TYW5
tRNA wybutosine-synthesizing protein 5

3

1

High-throughput

0.609

High

160805

TOR1B
Torsin-1B

3

1

High-throughput

0.609

High

593570

GDC
Solute carrier family 25 member 16

3

11

High-throughput

0.609

High

627510

NMU
Neuromedin-U [Cleaved into: Neuromedin precursor-related peptide 36

3

2

High-throughput

0.609

High

627515

HBA
Hemoglobin subunit alpha

3

3

High-throughput

0.609

High

627527

LTBP1
Latent-transforming growth factor beta-binding protein 1

3

1

High-throughput

0.609

High

627533

TM201
Transmembrane protein 201

3

2

High-throughput

0.609

High

627556

P121A
Nuclear envelope pore membrane protein POM 121

3

3

High-throughput

0.609

High

627589

ORNT1
Mitochondrial ornithine transporter 1

3

13

High-throughput

0.609

High

627528

PDK1
[Pyruvate dehydrogenase

3

5

High-throughput

0.599

High

627553

VWCE
von Willebrand factor C and EGF domain-containing protein

2

4

High-throughput

0.574

High

627514

RL23
Large ribosomal subunit protein uL14

2

1

High-throughput

0.558

High

627525

MTX1
Metaxin-1

2

1

High-throughput

0.558

High

627543

PLPL6
Patatin-like phospholipase domain-containing protein 6

2

3

High-throughput

0.558

High

627554

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

2

1

High-throughput

0.558

High

627570

SFXN1
Sideroflexin-1

2

4

High-throughput

0.558

High

49585

GXLT2
Glucoside xylosyltransferase 2

1

5

High-throughput

0.536

High

249357

PLXC1
Plexin-C1

1

15

High-throughput

0.536

High

551948

ADT1
ADP/ATP translocase 1

1

8

High-throughput

0.536

High

616079

LAG3
Lymphocyte activation gene 3 protein

1

2

High-throughput

0.536

High

627508

ECE1
Endothelin-converting enzyme 1

1

9

High-throughput

0.536

High

627511

MA2A2
Alpha-mannosidase 2x

1

3

High-throughput

0.536

High

627531

SGCB
Beta-sarcoglycan

1

2

High-throughput

0.536

High

627541

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

1

10

High-throughput

0.536

High

627568

SEM6B
Semaphorin-6B

1

10

High-throughput

0.536

High

627578

CHSTC
Carbohydrate sulfotransferase 12

1

10

High-throughput

0.536

High

627580

CC50A
Cell cycle control protein 50A

1

6

High-throughput

0.536

High

627519

NUCB1
Nucleobindin-1

1

2

High-throughput

0.489

High

627522

FSTL1
Follistatin-related protein 1

1

1

High-throughput

0.489

High

627534

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

6

High-throughput

0.489

High

627558

SFXN2
Sideroflexin-2

1

4

High-throughput

0.489

High

627562

ADPGK
ADP-dependent glucokinase

1

1

High-throughput

0.489

High

627564

S2533
Solute carrier family 25 member 33

1

10

High-throughput

0.489

High

627565

T106C
Transmembrane protein 106C

1

17

High-throughput

0.489

High

627513

TM50B
Transmembrane protein 50B

1

3

High-throughput

0.481

High

627501

NF1
Neurofibromin

1

2

High-throughput

0.479

High

627518

AT2C1
Calcium-transporting ATPase type 2C member 1

1

11

High-throughput

0.479

High

627561

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

3

High-throughput

0.479

High

627573

PCDH9
Protocadherin-9

1

3

High-throughput

0.479

High

627575

ABCB6
ATP-binding cassette sub-family B member 6

1

6

High-throughput

0.479

High

184114

RER1
Protein RER1

1

0

High-throughput

0.458

High

627520

SLC31
Amino acid transporter heavy chain SLC3A1

1

6

High-throughput

0.445

High

627537

S39A5
Zinc transporter ZIP5

1

15

High-throughput

0.445

High

627567

S12A5
Solute carrier family 12 member 5

1

3

High-throughput

0.445

High

295416

CNMD
Leukocyte cell-derived chemotaxin 1

1

1

High-throughput

0.439

High

346710

TM50A
Transmembrane protein 50A

1

3

High-throughput

0.439

High

380734

HBD
Hemoglobin subunit delta

1

3

High-throughput

0.437

High

627500

HXA5
Homeobox protein Hox-A5

1

3

High-throughput

0.437

High

627506

HXD13
Homeobox protein Hox-D13

1

1

High-throughput

0.437

High

627532

GPAT3
Glycerol-3-phosphate acyltransferase 3

1

4

High-throughput

0.437

High

627544

ASPM
Abnormal spindle-like microcephaly-associated protein

1

1

High-throughput

0.437

High

627555

MYO19
Unconventional myosin-XIX

1

3

High-throughput

0.437

High

627559

F210A
Protein FAM210A

1

1

High-throughput

0.437

High

627579

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

5

High-throughput

0.437

High

85093

B7Z207
Protein-serine/threonine kinase

1

5

High-throughput

0.407

High

627536

SAMD1
Sterile alpha motif domain-containing protein 1

3

0

High-throughput

0.347

High

627563

CQ080
Mitochondrial nucleoid-associated protein 1

3

0

High-throughput

0.347

High

627581

INT7
Integrator complex subunit 7

3

0

High-throughput

0.347

High

627587

NOB1
RNA-binding protein NOB1

3

0

High-throughput

0.347

High

627504

GALA
Galanin peptides [Cleaved into: Galanin; Galanin message-associated peptide

3

0

High-throughput

0.339

High

328225

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

2

0

High-throughput

0.318

High

627591

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

2

0

High-throughput

0.318

High

286520

SG2A1
Mammaglobin-B

1

0

High-throughput

0.279

Low

627546

NPW
Neuropeptide W

1

0

High-throughput

0.279

Low

627574

BPIA1
BPI fold-containing family A member 1

1

0

High-throughput

0.279

Low

627524

MYO9B
Unconventional myosin-IXb

1

0

High-throughput

0.249

Low

627560

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

627588

DIM1
Dimethyladenosine transferase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025