HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: CHD1 (Q7KU24)
Chromodomain-helicase-DNA-binding protein 1 (CHD-1) (EC 3.6.4.-) (ATP-dependent helicase Chd1)
Gene: CHD1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.681

Property	Details
Experiments	21177652
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Chromo~Histone, Histone~SNF2-rel_dom
Common GO terms	GO:0000785 - chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 1883
+	Hs
		160175 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		CHD2_HUMAN (52-1875): 0: 997: 42.97
+	Hs
		998897 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD7_HUMAN (19-1874): 0: 987: 21.72
+	Hs
		998832 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD8_HUMAN (4-1883): 0: 986: 21.74
+	Hs
		160068 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD1_HUMAN (108-1775): 0: 951: 45.59
+	Hs
		160071 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		CHD1_HUMAN (108-1775): 0: 951: 45.59
+	Hs
		160094 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CHD1_HUMAN (108-1775): 0: 951: 45.59
+	Mm
		820799 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		CHD1_MOUSE (108-1775): 0: 946: 45.11
+	Hs
		998575 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD6_HUMAN (15-1657): 0: 929: 22.32
+	Hs
		998258 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD3_HUMAN (110-1671): 0: 928: 24.49
+	Hs
		1161954 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CHD6_HUMAN (15-1657): 0: 929: 22.32
+	Mm
		59101 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		CHD5_MOUSE (86-1697): 0: 922: 22.46
+	Hs
		998577 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD5_HUMAN (214-1507): 0: 914: 25.25
+	Hs
		1161955 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CHD5_HUMAN (214-1507): 0: 914: 25.25
+	Hs
		998324 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD4_HUMAN (101-1664): 0: 880: 24.05
+	Hs
		1132727 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CHD4_HUMAN (101-1664): 0: 880: 24.05
+	Mm
		999034 H31_MOUSE (1-136): 3.1e-62: 188: 99.27		SMCA5_MOUSE (395-1417): 0: 794: 27.24
+	Mm
		1017370 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		SMCA5_MOUSE (395-1417): 0: 794: 27.24
+	Hs
		243594 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SMCA5_HUMAN (385-1417): 0: 792: 27.17
+	Hs
		243599 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		SMCA5_HUMAN (385-1417): 0: 792: 27.17
+	Hs
		703289 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		SMCA1_HUMAN (393-1409): 0: 784: 27.39