HitPredict

Interactor 1: H3 (P02299)
Histone H3
Gene: H3, His3;

Interactor 2: AURKB (Q9VKN7)
Aurora kinase B (EC 2.7.11.1) (IPL1/Aurora-like protein kinase) (Serine/threonine-protein kinase Ial) (Serine/threonine-protein kinase aurora-B)
Gene: aurB

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.24	0.50	0.348

Property	Details
Experiments	unassigned4
Identification Methods	experimental interaction detection
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Dm			1 329
+	Hs
		728575 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		AKT2_HUMAN (1-328): 2.02e-138: 402: 27.46
+	Hs
		728162 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		AKT1_HUMAN (15-328): 1.31e-134: 392: 28.26
+	Hs
		651645 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KAPCB_HUMAN (31-327): 7.51e-134: 386: 30.46
+	Hs
		651648 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		KAPCB_HUMAN (31-327): 7.51e-134: 386: 30.46
+	Hs
		651676 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		KAPCB_HUMAN (31-327): 7.51e-134: 386: 30.46
+	Hs
		170076 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		AURKA_HUMAN (1-325): 1.14e-130: 380: 43.47
+	Hs
		170171 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		AURKA_HUMAN (1-325): 1.14e-130: 380: 43.47
+	Mm
		1017345 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		AURKA_MOUSE (2-326): 9.19e-130: 377: 44.00
+	Dm
		381703 H3_DROME (1-136): 6.24e-61: 185: 100.00		Q27393_DROME (35-309): 5.6e-125: 366: 49.09
+	Hs
		998953 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		AURKC_HUMAN (52-307): 1.3e-95: 287: 51.56
+	Mm
		266584 H33_MOUSE (1-136): 2.57e-61: 186: 97.06		AURKB_MOUSE (44-307): 3.08e-93: 282: 50.00
+	Hs
		998674 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		AURKB_HUMAN (52-307): 2e-90: 275: 52.34
+	Hs
		1017111 H33_HUMAN (1-136): 2.57e-61: 186: 97.06		AURKB_HUMAN (52-307): 2e-90: 275: 52.34
+	Hs
		1161998 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		AURKB_HUMAN (52-307): 2e-90: 275: 52.34
+	Hs
		1258913 H32_HUMAN (1-136): 6.24e-61: 185: 100.00		AURKB_HUMAN (52-307): 2e-90: 275: 52.34
+	At
		947621 H31_ARATH (1-136): 1.71e-60: 184: 97.06		AUR1_ARATH (48-305): 1.19e-89: 271: 51.54
+	Hs
		1239465 H3C_HUMAN (1-136): 5.27e-58: 177: 94.12		AURKB_HUMAN (52-307): 2e-90: 275: 52.34
+	Hs
		883655 CENPA_HUMAN (9-133): 2.87e-44: 143: 50.00		AURKB_HUMAN (52-307): 2e-90: 275: 52.34
+	Sc
		808655 H3_YEAST (1-136): 1.23e-55: 171: 88.97		AURK_YEAST (3-305): 7.21e-73: 231: 42.81
+	Sc
		779228 CENPA_YEAST (18-134): 2.58e-43: 143: 56.67		AURK_YEAST (3-305): 7.21e-73: 231: 42.81