HitPredict

Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~Ig_3
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 821
+	Hs
		382280 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR1_HUMAN (1-820): 0: 772: 71.17
+	Hs
		382308 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FGFR4_HUMAN (22-810): 0: 684: 55.86
+	Hs
		382433 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31
+	Hs
		382268 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		RET_HUMAN (228-816): 2.74e-144: 455: 34.26
+	Hs
		382259 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04
+	Hs
		488237 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31
+	Hs
		570320 HLAG_HUMAN (1-338): 2.35e-151: 431: 82.84		ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29
+	Hs
		488193 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29
+	Hs
		673955 HLAF_HUMAN (4-348): 3.64e-141: 406: 80.29		NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31
+	Hs
		533140 HLAE_HUMAN (20-357): 5.1e-143: 411: 78.99		ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29
+	Hs
		382331 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15
+	Hs
		488144 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		FLT3_HUMAN (342-800): 5.44e-85: 293: 36.15
+	Hs
		382329 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62
+	Hs
		382400 HLAA_HUMAN (1-365): 1.3e-177: 499: 100.00		TYRO3_HUMAN (167-367): 4.11e-12: 72.1: 22.55
+	Hs
		169158 HLAB_HUMAN (1-362): 3.05e-157: 447: 85.64		MUSK_HUMAN (34-396): 6.41e-25: 113: 18.43
+	Hs
		169162 HLAC_HUMAN (1-364): 2.2e-150: 430: 80.27		MUSK_HUMAN (34-396): 6.41e-25: 113: 18.43