Interactor 1: KU80 (Q04437)
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku80) (High affinity DNA-binding factor subunit 2) (Yeast Ku80)
Gene: YKU80

Interactor 2: DNLI4 (Q08387)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase II) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: DNL4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 16314503
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT~Ku, BRCT_2~Ku, DNA_ligase_A_N~Ku_N
Common GO terms GO:0003677 - DNA binding
GO:0005524 - ATP binding
GO:0006303 - double-strand break repair via nonhomologous end joining
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 629
Sc

1 944
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs

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Last updated: 15 Jul 2024