HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	12620224, 28068333, 17049045, 34056863, 37968396, 14761951, 11343701, 14690608, 22199229
Identification Methods	pull down, affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Sc			1 686
+	Sp
		480426 H4_SCHPO (18-103): 2.81e-41: 133: 90.70		YK82_SCHPO (6-672): 2.45e-111: 354: 24.89
+	Sc
		382376 H4_YEAST (1-103): 5.31e-47: 147: 100.00		BDF2_YEAST (84-615): 7.77e-82: 273: 38.04
+	Dm
		1014781 H4_DROME (18-103): 2.43e-41: 133: 90.70		Q4V5A7_DROME (123-684): 1.01e-67: 236: 13.88
+	Sc
		382291 H4_YEAST (1-103): 5.31e-47: 147: 100.00		RSC4_YEAST (105-686): 7.61e-56: 203: 15.22
+	Hs
		639705 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38
+	Hs
		980379 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60
+	Hs
		979968 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		TAF1L_HUMAN (115-578): 1.17e-53: 202: 14.62
+	Hs
		979908 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		PB1_HUMAN (91-664): 2.89e-39: 158: 12.56
+	Hs
		980078 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		CBP_HUMAN (249-418): 1.17e-36: 150: 25.73
+	Zm
		19410 A0A1D6IAU4_MAIZE (18-103): 9.8e-45: 142: 89.54		A0A1D6HCG5_MAIZE (143-321): 6.07e-31: 131: 26.26
+	Hs
		980051 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		PHIP_HUMAN (108-640): 1.65e-30: 130: 12.78
+	Mm
		980667 H4_MOUSE (18-103): 1.93e-41: 133: 90.70		BRDT_MOUSE (299-559): 1.05e-28: 124: 20.80
+	Hs
		674123 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		BRD2_HUMAN (297-569): 2.1e-27: 120: 17.83
+	Hs
		979687 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60
+	Hs
		259745 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		BRD4_HUMAN (267-427): 2.87e-26: 117: 26.71
+	Hs
		979856 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		BRWD3_HUMAN (208-656): 3.9e-21: 101: 12.09
+	Dm
		567628 H4_DROME (18-103): 2.43e-41: 133: 90.70		FSH_DROME (508-654): 1.72e-17: 89.6: 20.81
+	Sc
		382306 H4_YEAST (1-103): 5.31e-47: 147: 100.00		GCN5_YEAST (124-255): 2.18e-09: 62: 31.82
+	Hs
		980502 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		BAZ2B_HUMAN (307-420): 7.78e-13: 74.3: 39.47
+	Hs
		979558 H4_HUMAN (18-103): 1.93e-41: 133: 90.70		EP300_HUMAN (303-417): 1.54e-09: 63.5: 37.61