HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: U2AF2 (P26368)
Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Gene: U2AF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25921289
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 475
+	Hs
		384864 NTRK1_HUMAN (1-796): 0: 621: 100.00		SART3_HUMAN (10-377): 4.33e-86: 285: 22.52
+	Hs
		384903 NTRK1_HUMAN (1-796): 0: 621: 100.00		ELAV1_HUMAN (149-471): 2.84e-73: 235: 14.79
+	Hs
		384841 NTRK1_HUMAN (1-796): 0: 621: 100.00		ELAV3_HUMAN (127-472): 9.26e-67: 220: 13.98
+	Hs
		384837 NTRK1_HUMAN (1-796): 0: 621: 100.00		RBM39_HUMAN (10-471): 4.93e-48: 175: 19.16
+	Hs
		384300 NTRK1_HUMAN (1-796): 0: 621: 100.00		ELAV4_HUMAN (88-342): 7.66e-39: 146: 13.33
+	Hs
		384351 NTRK1_HUMAN (1-796): 0: 621: 100.00		TIA1_HUMAN (253-475): 5.63e-36: 138: 15.70
+	Hs
		385676 NTRK1_HUMAN (1-796): 0: 621: 100.00		PUF60_HUMAN (92-474): 7.84e-23: 103: 21.50
+	Hs
		384775 NTRK1_HUMAN (1-796): 0: 621: 100.00		PABP4_HUMAN (41-251): 2.07e-19: 93: 12.78
+	Hs
		384175 NTRK1_HUMAN (1-796): 0: 621: 100.00		PABP1_HUMAN (41-247): 3.26e-19: 92.6: 14.35
+	Mm
		546300 NTRK2_MOUSE (12-796): 2.75e-174: 524: 47.32		ELAV4_MOUSE (88-342): 7.66e-39: 146: 13.33
+	Rn
		88882 INSR_RAT (493-777): 7.31e-66: 241: 41.95		D4A233_RAT (41-238): 7.4e-17: 84.9: 13.55