HitPredict

Interactor 1: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Interactor 2: US6NL (Q92738)
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
Gene: USP6NL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0043547 - positive regulation of GTPase activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 796 Hs			1 828
+	Hs
		508130 FGFR1_HUMAN (195-794): 0: 545: 26.34		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		1083876 NTRK2_HUMAN (12-796): 1.28e-176: 529: 46.72		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		1081555 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		608070 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		601560 FGFR2_HUMAN (87-794): 5.67e-159: 484: 22.55		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		872469 EPHA5_HUMAN (409-788): 2.48e-111: 365: 30.36		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		968329 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		968449 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		385345 NTRK1_HUMAN (1-796): 0: 621: 100.00		SGSM3_HUMAN (7-508): 8.25e-110: 355: 19.22
+	Hs
		384945 NTRK1_HUMAN (1-796): 0: 621: 100.00		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		385771 NTRK1_HUMAN (1-796): 0: 621: 100.00		RBGP1_HUMAN (59-586): 1.36e-90: 310: 19.46
+	Hs
		232625 NTRK1_HUMAN (1-796): 0: 621: 100.00		TBCD4_HUMAN (1-455): 1.43e-88: 307: 19.40
+	Hs
		234364 FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59		EVI5_HUMAN (17-591): 7.71e-114: 367: 19.55
+	Hs
		508039 FGFR1_HUMAN (195-794): 0: 545: 26.34		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		1081500 NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		232666 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		TBCD4_HUMAN (1-455): 1.43e-88: 307: 19.40
+	Hs
		968317 ROR1_HUMAN (515-783): 1.16e-72: 257: 46.89		TBCD1_HUMAN (2-455): 5.05e-88: 304: 20.93
+	Hs
		968396 ROR2_HUMAN (515-783): 2.79e-66: 239: 43.91		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87