HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	27249653
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding GO:0033077 - T cell differentiation in thymus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1043
+	Hs
		387147 P53_HUMAN (1-393): 0: 619: 100.00		COP1_HUMAN (278-587): 9.57e-53: 200: 20.48
+	Hs
		386946 P53_HUMAN (1-393): 0: 619: 100.00		TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59
+	Hs
		386017 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59
+	Hs
		386629 P53_HUMAN (1-393): 0: 619: 100.00		TRI26_HUMAN (278-501): 1.93e-37: 150: 16.52
+	Hs
		387560 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05
+	Hs
		387456 P53_HUMAN (1-393): 0: 619: 100.00		TRI31_HUMAN (278-550): 3.89e-33: 135: 13.26
+	Hs
		387282 P53_HUMAN (1-393): 0: 619: 100.00		RN125_HUMAN (284-416): 1.01e-33: 131: 28.57
+	Hs
		387804 P53_HUMAN (1-393): 0: 619: 100.00		TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00
+	Hs
		387188 P53_HUMAN (1-393): 0: 619: 100.00		RN138_HUMAN (288-386): 3.15e-30: 122: 25.00
+	Hs
		387156 P53_HUMAN (1-393): 0: 619: 100.00		LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66
+	Hs
		386071 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (79-206): 1.07e-12: 73.7: 12.40
+	Hs
		386227 P53_HUMAN (1-393): 0: 619: 100.00		BRCA1_HUMAN (291-361): 2.22e-09: 63.9: 28.77
+	Hs
		175834 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		BRCA1_HUMAN (291-361): 2.22e-09: 63.9: 28.77
+	Hs
		749852 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		BRCA1_HUMAN (291-361): 2.22e-09: 63.9: 28.77