HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: CRBG1 (Q9Y4K1)
Beta/gamma crystallin domain-containing protein 1 (Absent in melanoma 1 protein)
Gene: CRYBG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 2131
+	Hs
		437402 K2C8_HUMAN (69-431): 7.94e-131: 391: 36.44		CRBG1_HUMAN (1-2131): 0: 1109: 100.00
+	Hs
		1157269 AINX_HUMAN (66-401): 1.67e-91: 290: 58.11		CRBG1_HUMAN (1-2131): 0: 1109: 100.00
+	Hs
		475085 VIME_HUMAN (34-402): 6.77e-84: 270: 49.59		CRBG1_HUMAN (1-2131): 0: 1109: 100.00
+	Hs
		451468 NFM_HUMAN (82-409): 4.23e-72: 249: 54.71		CRBG1_HUMAN (1-2131): 0: 1109: 100.00
+	Hs
		437218 K2C8_HUMAN (69-431): 7.94e-131: 391: 36.44		CRBG3_HUMAN (584-2129): 0: 794: 22.86
+	Hs
		451144 NFL_HUMAN (1-543): 1.02e-150: 444: 100.00		ANK2_HUMAN (132-1488): 1.22e-26: 122: 8.84
+	Hs
		451110 NFL_HUMAN (1-543): 1.02e-150: 444: 100.00		NFH_HUMAN (109-491): 3.26e-13: 77.5: 15.54
+	Rn
		599260 NFL_RAT (1-543): 2.86e-147: 436: 94.67		NFH_RAT (134-493): 2.15e-09: 65.2: 17.31
+	Hs
		437094 K2C8_HUMAN (69-431): 7.94e-131: 391: 36.44		APC_HUMAN (1-1269): 3.44e-14: 81.1: 8.66
+	Hs
		437288 K2C8_HUMAN (69-431): 7.94e-131: 391: 36.44		TITIN_HUMAN (2-818): 4.16e-12: 74.6: 7.41
+	Hs
		1030645 AINX_HUMAN (66-401): 1.67e-91: 290: 58.11		ANK2_HUMAN (132-1488): 1.22e-26: 122: 8.84
+	Hs
		474621 VIME_HUMAN (34-402): 6.77e-84: 270: 49.59		ANK2_HUMAN (132-1488): 1.22e-26: 122: 8.84
+	Hs
		451367 NFM_HUMAN (82-409): 4.23e-72: 249: 54.71		ANK2_HUMAN (132-1488): 1.22e-26: 122: 8.84
+	Hs
		551616 AINX_HUMAN (66-401): 1.67e-91: 290: 58.11		NFH_HUMAN (109-491): 3.26e-13: 77.5: 15.54
+	Hs
		833250 PERI_HUMAN (9-401): 1.78e-69: 232: 48.12		ANK2_HUMAN (132-1488): 1.22e-26: 122: 8.84
+	Hs
		474978 VIME_HUMAN (34-402): 6.77e-84: 270: 49.59		TARA_HUMAN (548-1431): 3.79e-11: 71.2: 10.63
+	Hs
		451320 NFM_HUMAN (82-409): 4.23e-72: 249: 54.71		NFH_HUMAN (109-491): 3.26e-13: 77.5: 15.54
+	Hs
		451423 NFM_HUMAN (82-409): 4.23e-72: 249: 54.71		TITIN_HUMAN (2-818): 4.16e-12: 74.6: 7.41
+	Hs
		551604 DESM_HUMAN (69-402): 4.33e-72: 239: 53.89		NFH_HUMAN (109-491): 3.26e-13: 77.5: 15.54
+	Hs
		566334 K2C5_HUMAN (55-403): 3.07e-59: 208: 31.53		APC_HUMAN (1-1269): 3.44e-14: 81.1: 8.66