Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1
Interactor 2: BTK (Q06187)
Tyrosine-protein kinase BTK (EC 2.7.10.2) (Agammaglobulinemia tyrosine kinase) (ATK) (B-cell progenitor kinase) (BPK) (Bruton tyrosine kinase)
Gene: BTK
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21080425 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PH~SH3_1, PK_Tyr_Ser-Thr~SH3_1, SH2~SH3_1, SH3_1~SH3_1 |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025