HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: CCAR1 (Q8IX12)
Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain)
Gene: CCAR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32807901, 18382127
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0043065 - positive regulation of apoptotic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1150
+	Hs
		387084 P53_HUMAN (1-393): 0: 619: 100.00		CCAR2_HUMAN (667-1140): 1.1e-32: 139: 27.11
+	Hs
		387815 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (589-1150): 5.13e-18: 92.4: 11.95
+	Hs
		387710 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (420-1149): 1.29e-16: 87.8: 8.49
+	Hs
		386212 P53_HUMAN (1-393): 0: 619: 100.00		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03