HitPredict

Interactor 1: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 760 Hs			1 232
+	Hs
		390520 TFR1_HUMAN (1-760): 0: 971: 100.00		RND3_HUMAN (1-232): 9.61e-101: 294: 58.20
+	Hs
		390498 TFR1_HUMAN (1-760): 0: 971: 100.00		RND2_HUMAN (12-232): 9.66e-80: 240: 53.15
+	Hs
		390529 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC1_HUMAN (11-200): 6.09e-79: 237: 38.42
+	Hs
		390537 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOG_HUMAN (11-198): 4.17e-78: 234: 37.77
+	Hs
		390443 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC2_HUMAN (11-201): 8.33e-76: 229: 38.22
+	Hs
		390513 TFR1_HUMAN (1-760): 0: 971: 100.00		RAC3_HUMAN (11-188): 6.07e-76: 229: 39.89
+	Hs
		390519 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOA_HUMAN (15-197): 9.94e-75: 226: 43.17
+	Hs
		390514 TFR1_HUMAN (1-760): 0: 971: 100.00		CDC42_HUMAN (11-198): 1.38e-74: 225: 37.23
+	Hs
		390425 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOC_HUMAN (13-184): 4.61e-50: 163: 46.51
+	Hs
		390526 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOB_HUMAN (13-190): 2.92e-49: 161: 44.94
+	Hs
		126429 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOD_HUMAN (6-189): 1.8e-48: 160: 40.76
+	Hs
		390770 TFR1_HUMAN (1-760): 0: 971: 100.00		RHOF_HUMAN (1-189): 2.34e-44: 149: 40.21