HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.937

The method score is based on:

Property Details
Experiments 19536198, 26217697, 15766533, 25452130, 24488121, 31399574
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HATPase_c_3~HSP70, HSP70~HSP90
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 709
Sc

1 613
+ Sc
+ Sc
+ Sc
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Gg
+ Sc
+ Gg
+ Ce
+ Hs
+ Sc
+ Sc
+ Ca

Service provided by Combinatics, Japan

Last updated: 11Aug2025