HitPredict

Interactor 1: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Interactor 2: PA2GA (P14555)
Phospholipase A2, membrane associated (EC 3.1.1.4) (GIIC sPLA2) (Group IIA phospholipase A2) (Non-pancreatic secretory phospholipase A2) (NPS-PLA2) (Phosphatidylcholine 2-acylhydrolase 2A)
Gene: PLA2G2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	18635536, 25398877
Identification Methods	pull down, enzyme linked immunosorbent assay, scintillation proximity assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 788 Hs			1 144
+	Hs
		403760 ITB1_HUMAN (10-787): 0: 727: 43.47		PA2GA_HUMAN (1-144): 6.19e-56: 173: 100.00