Interactor 1: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Interactor 2: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 11807098, 25849143
Identification Methods two hybrid, surface plasmon resonance, nuclear magnetic resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Filamin~Integrin_b_cyt
Common GO terms GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005925 - focal adhesion
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 788
Hs

1 2647
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024