HitPredict

Interactor 1: S10A8 (P05109)
Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)
Gene: S100A8

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	26618866, 31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 93 Hs			1 1480
+	Hs
		529371 HORN_HUMAN (2-89): 7.34e-30: 112: 25.00		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528643 S10AB_HUMAN (2-93): 1.23e-31: 108: 26.04		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		416344 S10A9_HUMAN (2-88): 5.5e-28: 99.1: 26.09		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529220 FILA2_HUMAN (2-89): 4.61e-25: 99.1: 29.35		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528867 S10AA_HUMAN (1-93): 5.15e-28: 98.7: 25.77		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		416559 S10A6_HUMAN (1-88): 9.59e-27: 95.3: 24.44		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528538 FILA_HUMAN (2-90): 4.67e-19: 81.8: 27.96		CFTR_HUMAN (1-1480): 0: 1031: 100.00