Interactor 1: KAPCA (P05132)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: Prkaca
Interactor 2: KAP3 (P31324)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: Prkar2b
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.946 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26158466, 21614075, 22323819, 26278174, 24464040 |
| Identification Methods | surface plasmon resonance, molecular sieving, protein kinase assay, anti tag coimmunoprecipitation, solid phase assay, x-ray crystallography, x ray scattering, transmission electron microscopy, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~cNMP_binding, Pkinase~RIIa |
| Common GO terms | GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005952 - cAMP-dependent protein kinase complex and 9 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
