HitPredict

Interactor 1: HEM2 (P05373)
Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)
Gene: HEM2

Interactor 2: HEM2 (P05373)
Delta-aminolevulinic acid dehydratase (ALADH) (EC 4.2.1.24) (Porphobilinogen synthase)
Gene: HEM2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.791

The method score is based on:

Property Details
Experiments 11283351, 18467557
Identification Methods two hybrid, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ALAD~ALAD
Common GO terms GO:0004655 - porphobilinogen synthase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006782 - protoporphyrinogen IX biosynthetic process
and 2 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 342
Sc

1 342
+ Mm
+ Dm
+ Ec
+ Mt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024