HitPredict

Interactor 1: JUN (P05412)
Transcription factor Jun (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (Transcription factor AP-1 subunit Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)
Gene: JUN

Interactor 2: AF17 (P55198)
Protein AF-17 (ALL1-fused gene from chromosome 17 protein)
Gene: MLLT6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 331 Hs			1 1093
+	Hs
		568081 JUND_HUMAN (5-331): 5.93e-47: 163: 45.86		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		547760 ATF2_HUMAN (47-331): 1.64e-38: 144: 17.33		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		568255 ATF7_HUMAN (49-328): 1.94e-33: 130: 23.02		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		876601 CEBPE_HUMAN (112-314): 1.46e-26: 107: 17.35		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		876591 CREB5_HUMAN (209-329): 7.99e-23: 100: 26.40		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		862899 CEBPG_HUMAN (215-318): 4.54e-10: 59.3: 22.86		AF17_HUMAN (1-1093): 1.44e-115: 385: 100.00
+	Hs
		401362 JUN_HUMAN (1-331): 8.11e-87: 266: 100.00		MUC1_HUMAN (314-1082): 1.9e-41: 168: 13.53
+	Hs
		299037 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		PHF14_HUMAN (7-320): 1.35e-60: 226: 25.08
+	Hs
		554262 CEBPB_HUMAN (233-312): 1.98e-09: 60.1: 20.73		MUC1_HUMAN (314-1082): 1.9e-41: 168: 13.53