HitPredict

Interactor 1: ITB1 (P05556)
Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29)
Gene: ITGB1

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016477 - cell migration GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 798 Hs			1 232
+	Hs
		403846 ITB1_HUMAN (1-798): 0: 794: 100.00		RND3_HUMAN (1-232): 1.75e-100: 293: 58.20
+	Hs
		403842 ITB1_HUMAN (1-798): 0: 794: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		403831 ITB1_HUMAN (1-798): 0: 794: 100.00		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		403851 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		403841 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		403849 ITB1_HUMAN (1-798): 0: 794: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		403762 ITB1_HUMAN (1-798): 0: 794: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		403845 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		403858 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Hs
		403739 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		403850 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120276 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		403970 ITB1_HUMAN (1-798): 0: 794: 100.00		RHOF_HUMAN (1-189): 2.33e-44: 149: 40.21
+	Hs
		574521 ITB5_HUMAN (19-792): 0: 660: 42.64		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		574519 ITB5_HUMAN (19-792): 0: 660: 42.64		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545199 ITB5_HUMAN (19-792): 0: 660: 42.64		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		436152 ITB5_HUMAN (19-792): 0: 660: 42.64		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		574520 ITB5_HUMAN (19-792): 0: 660: 42.64		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		639922 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		639924 ITB8_HUMAN (7-680): 3.15e-167: 504: 36.32		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94