HitPredict

Interactor 1: GCR (P04150)
Glucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)
Gene: NR3C1

Interactor 2: RYR2 (Q92736)
Ryanodine receptor 2 (RYR-2) (RyR2) (hRYR-2) (Cardiac muscle ryanodine receptor) (Cardiac muscle ryanodine receptor-calcium release channel) (Type 2 ryanodine receptor)
Gene: RYR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31182584
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 4967
+	Hs
		403821 GCR_HUMAN (1-777): 0: 913: 100.00		RYR1_HUMAN (1-4967): 0: 6993: 64.60
+	Hs
		641343 ESR2_HUMAN (286-769): 4.86e-108: 342: 21.34		RYR1_HUMAN (1-4967): 0: 6993: 64.60
+	Hs
		404056 GCR_HUMAN (1-777): 0: 913: 100.00		ITPR3_HUMAN (4713-4953): 2.12e-91: 337: 31.72
+	Hs
		403986 GCR_HUMAN (1-777): 0: 913: 100.00		HNRPU_HUMAN (1009-1391): 1.12e-82: 295: 15.61
+	Hs
		404355 GCR_HUMAN (1-777): 0: 913: 100.00		RANB9_HUMAN (1021-1404): 2.53e-68: 250: 17.88
+	Hs
		404125 GCR_HUMAN (1-777): 0: 913: 100.00		RN123_HUMAN (1084-1239): 3.31e-41: 171: 30.63
+	Hs
		396112 ESR1_HUMAN (263-760): 1.14e-130: 403: 23.06		ITPR3_HUMAN (4713-4953): 2.12e-91: 337: 31.72
+	Hs
		1128356 ESR2_HUMAN (286-769): 4.86e-108: 342: 21.34		ITPR2_HUMAN (4713-4953): 5.93e-99: 362: 31.94
+	Hs
		395923 ESR1_HUMAN (263-760): 1.14e-130: 403: 23.06		HNRPU_HUMAN (1009-1391): 1.12e-82: 295: 15.61
+	Hs
		396847 ESR1_HUMAN (263-760): 1.14e-130: 403: 23.06		HNRL1_HUMAN (965-1395): 1.01e-76: 278: 14.83
+	Hs
		1128445 ESR2_HUMAN (286-769): 4.86e-108: 342: 21.34		ITPR3_HUMAN (4713-4953): 2.12e-91: 337: 31.72
+	Hs
		396764 ESR1_HUMAN (263-760): 1.14e-130: 403: 23.06		RANB9_HUMAN (1021-1404): 2.53e-68: 250: 17.88
+	Hs
		442922 PRGR_HUMAN (232-777): 2.76e-109: 356: 40.00		HNRPU_HUMAN (1009-1391): 1.12e-82: 295: 15.61
+	Hs
		519950 ANDR_HUMAN (357-777): 7.83e-108: 352: 45.60		HNRPU_HUMAN (1009-1391): 1.12e-82: 295: 15.61
+	Hs
		520343 ANDR_HUMAN (357-777): 7.83e-108: 352: 45.60		HNRL1_HUMAN (965-1395): 1.01e-76: 278: 14.83
+	Hs
		520556 RARA_HUMAN (316-759): 6.46e-106: 334: 19.60		HNRPU_HUMAN (1009-1391): 1.12e-82: 295: 15.61
+	Mm
		542876 RARA_MOUSE (316-759): 2.74e-105: 332: 19.82		HNRPU_MOUSE (1009-1391): 1.43e-82: 293: 15.37
+	Hs
		520311 ANDR_HUMAN (357-777): 7.83e-108: 352: 45.60		RANB9_HUMAN (1021-1404): 2.53e-68: 250: 17.88
+	Hs
		396613 ESR1_HUMAN (263-760): 1.14e-130: 403: 23.06		DDX1_HUMAN (1097-1232): 2.5e-17: 92.1: 26.47
+	Hs
		520231 ANDR_HUMAN (357-777): 7.83e-108: 352: 45.60		DDX1_HUMAN (1097-1232): 2.5e-17: 92.1: 26.47