HitPredict

Interactor 1: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Interactor 2: UBS3B (Q8TF42)
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Gene: UBASH3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 483 Hs			1 649
+	Hs
		1205248 K2C73_HUMAN (1-405): 2.21e-86: 277: 54.82		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		1140440 K2C79_HUMAN (8-415): 2.02e-76: 250: 57.39		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		380504 K2C6B_HUMAN (56-405): 2.25e-66: 225: 70.46		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		531608 K2C5_HUMAN (56-405): 9.54e-66: 223: 71.02		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		359518 K2C6A_HUMAN (56-405): 8.09e-65: 220: 70.74		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		883376 KRT35_HUMAN (5-402): 8.85e-64: 215: 25.31		UBS3A_HUMAN (12-643): 0: 947: 43.37
+	Hs
		883337 K1H2_HUMAN (88-402): 1.27e-62: 212: 27.22		UBS3A_HUMAN (12-643): 0: 947: 43.37
+	Hs
		444533 K2C7_HUMAN (1-464): 4.13e-154: 448: 60.34		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924469 KRT83_HUMAN (12-418): 1.84e-89: 283: 53.07		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924576 KRT81_HUMAN (12-418): 1.03e-88: 282: 53.07		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		213936 KRT86_HUMAN (12-418): 3.09e-87: 277: 53.32		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924679 K2C73_HUMAN (1-405): 2.21e-86: 277: 54.82		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Mm
		1060206 Q148Q7_MOUSE (2-405): 3.9e-80: 260: 67.33		GRB2_MOUSE (156-319): 3.38e-45: 161: 21.56
+	Mm
		1141145 Q8BIS2_MOUSE (2-405): 2.75e-80: 260: 67.33		GRB2_MOUSE (156-319): 3.38e-45: 161: 21.56
+	Hs
		924895 KRT82_HUMAN (20-440): 2.98e-78: 255: 52.26		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		531551 K2C5_HUMAN (56-405): 9.54e-66: 223: 71.02		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		359480 K2C6A_HUMAN (56-405): 8.09e-65: 220: 70.74		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		280786 KRT36_HUMAN (5-450): 1.51e-63: 215: 23.49		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		409046 K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924741 KRT35_HUMAN (5-402): 8.85e-64: 215: 25.31		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56