HitPredict

Interactor 1: EPHB2 (P54763)
Ephrin type-B receptor 2 (EC 2.7.10.1) (Neural kinase) (Nuk receptor tyrosine kinase) (Tyrosine-protein kinase receptor EPH-3) (Tyrosine-protein kinase receptor SEK-3) [Cleaved into: EphB2/CTF1; EphB2/CTF2]
Gene: EPHB2

Interactor 2: GRIP1 (Q925T6)
Glutamate receptor-interacting protein 1 (GRIP-1)
Gene: GRIP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.42	1.00	0.653

Property	Details
Experiments	9883737
Identification Methods	two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0045211 - postsynaptic membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 986 Mm			1 1127
+	Hs
		710820 EPHB2_HUMAN (20-985): 0: 1227: 99.59		PTN13_HUMAN (21-531): 7.1e-26: 118: 13.60
+	Hs
		710831 EPHB2_HUMAN (20-985): 0: 1227: 99.59		SCRIB_HUMAN (672-828): 6.43e-15: 82.2: 23.81
+	Hs
		710866 EPHB2_HUMAN (20-985): 0: 1227: 99.59		LNX1_HUMAN (770-1120): 8.68e-13: 74.6: 12.64
+	Hs
		710901 EPHB2_HUMAN (20-985): 0: 1227: 99.59		LIN7C_HUMAN (149-246): 1.86e-09: 60.5: 35.71
+	Hs
		1090129 EPHA7_HUMAN (6-986): 0: 1147: 57.13		PTN13_HUMAN (21-531): 7.1e-26: 118: 13.60
+	Hs
		932061 EPHA4_HUMAN (6-986): 0: 1141: 58.19		PTN13_HUMAN (21-531): 7.1e-26: 118: 13.60
+	Hs
		931840 EPHA5_HUMAN (6-978): 0: 1135: 55.98		PTN13_HUMAN (21-531): 7.1e-26: 118: 13.60
+	Hs
		710622 EPHA3_HUMAN (16-977): 0: 1120: 56.34		PTN13_HUMAN (21-531): 7.1e-26: 118: 13.60
+	Hs
		1122235 EPHA7_HUMAN (6-986): 0: 1147: 57.13		SCRIB_HUMAN (672-828): 6.43e-15: 82.2: 23.81
+	Hs
		932093 EPHA4_HUMAN (6-986): 0: 1141: 58.19		MAGI2_HUMAN (3-297): 3e-15: 83.1: 14.38
+	Hs
		1147388 EPHA7_HUMAN (6-986): 0: 1147: 57.13		LNX1_HUMAN (770-1120): 8.68e-13: 74.6: 12.64
+	Hs
		1147375 EPHA7_HUMAN (6-986): 0: 1147: 57.13		LNX2_HUMAN (811-1107): 1.01e-11: 71.3: 16.21
+	Hs
		1091501 EPHA7_HUMAN (6-986): 0: 1147: 57.13		DLG1_HUMAN (977-1114): 1.91e-11: 70.5: 19.46
+	Hs
		932103 EPHA4_HUMAN (6-986): 0: 1141: 58.19		LNX1_HUMAN (770-1120): 8.68e-13: 74.6: 12.64
+	Hs
		932062 EPHA4_HUMAN (6-986): 0: 1141: 58.19		DLG1_HUMAN (977-1114): 1.91e-11: 70.5: 19.46
+	Hs
		931816 EPHB3_HUMAN (17-986): 0: 1133: 70.61		LNX1_HUMAN (770-1120): 8.68e-13: 74.6: 12.64
+	Hs
		1147448 EPHA7_HUMAN (6-986): 0: 1147: 57.13		LIN7C_HUMAN (149-246): 1.86e-09: 60.5: 35.71
+	Hs
		931842 EPHA5_HUMAN (6-978): 0: 1135: 55.98		DLG1_HUMAN (977-1114): 1.91e-11: 70.5: 19.46
+	Hs
		932143 EPHA4_HUMAN (6-986): 0: 1141: 58.19		LIN7C_HUMAN (149-246): 1.86e-09: 60.5: 35.71
+	Hs
		931905 EPHA5_HUMAN (6-978): 0: 1135: 55.98		LIN7C_HUMAN (149-246): 1.86e-09: 60.5: 35.71