HitPredict

Interactor 1: KAPC (P05986)
cAMP-dependent protein kinase type 3 (PKA 3) (EC 2.7.11.11)
Gene: TPK3

Interactor 2: KAPA (P06244)
cAMP-dependent protein kinase type 1 (PKA 1) (EC 2.7.11.11) (CDC25-suppressing protein kinase) (PK-25)
Gene: TPK1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.899

The method score is based on:

Property Details
Experiments 11805837, 16319894, 37968396, 20489023
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0004679 - AMP-activated protein kinase activity
GO:0004691 - cAMP-dependent protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 8 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 398
Sc

1 397
+ Sc
+ Sc
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+ Hs
+ Hs
+ Hs
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+ Mm
+ Hs
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+ Ce

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Last updated: 15 Jul 2024