Interactor 1: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Interactor 2: OSBL8 (Q9BZF1)
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)
Gene: OSBPL8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 35384245
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr
Common GO terms GO:0016020 - membrane
GO:0046326 - positive regulation of glucose import
GO:0051897 - positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 1382
Hs

1 889
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024