HitPredict

Interactor 1: KAPA (P06244)
cAMP-dependent protein kinase type 1 (PKA 1) (EC 2.7.11.11) (CDC25-suppressing protein kinase) (PK-25)
Gene: TPK1

Interactor 2: KAPR (P07278)
cAMP-dependent protein kinase regulatory subunit (cAPK regulatory subunit) (Bypass of cyclase mutations protein 1) (Protein kinase A regulatory subunit) (PKA regulatory subunit)
Gene: BCY1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.987

The method score is based on:

Property Details
Experiments 16924114, 11283351, 10688190, 8386630, 11805837, 9811878, 16554755, 16319894, 34244791, 20489023, 21118957, 19364808, 22957732, 21925385, 18467557, 34999138, 37968396, 22419819, 16429126
Identification Methods two hybrid, two hybrid pooling approach, genetic interference, experimental interaction detection, anti tag coimmunoprecipitation, affinity chromatography technology, enzymatic study, protein complementation assay, pull down, dihydrofolate reductase reconstruction and 1 others

more...
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding, Pkinase~RIIa
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005952 - cAMP-dependent protein kinase complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 397
Sc

1 416
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Last updated: 15 Jul 2024