Interactor 1: CPNS1 (P04632)
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)
Gene: CAPNS1

Interactor 2: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 0.60 0.747

The method score is based on:

Property Details
Experiments 26496610, 28514442, 33961781, 36964131, 31839598, unassigned3799, 19712109
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, enzyme linked immunosorbent assay, protease assay
Interaction Type physical association, association, cleavage reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004198 - calcium-dependent cysteine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006508 - proteolysis
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 268
Hs

1 714
+ Hs
+ Hs
+ Rn
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+ Hs
+ Dm
+ Dm
+ Dm
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+ Dm
+ Hs
+ Ss
+ Hs

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Last updated: 11Aug2025