Interactor 1: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1
Interactor 2: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 36964131 |
| Identification Methods | enzymatic study |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Calpain_III~EF-hand_8, Calpain_III~Peptidase_C2, EF-hand_8~EF-hand_8, Peptidase_C2~Peptidase_C2 |
| Common GO terms | GO:0001533 - cornified envelope GO:0004198 - calcium-dependent cysteine-type endopeptidase activity GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0005737 - cytoplasm and 18 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025
