HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	32451438
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0035861 - site of double-strand break
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 245
+	Hs
		414915 P53_HUMAN (1-393): 0: 619: 100.00		TRAF6_HUMAN (12-245): 2.11e-33: 128: 16.25
+	Hs
		413727 P53_HUMAN (1-393): 0: 619: 100.00		TRI26_HUMAN (3-239): 1.51e-32: 125: 15.57
+	Hs
		413166 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (6-157): 1.66e-31: 122: 17.11
+	Hs
		414391 P53_HUMAN (1-393): 0: 619: 100.00		RN125_HUMAN (2-245): 6.67e-33: 121: 26.64
+	Hs
		414471 P53_HUMAN (1-393): 0: 619: 100.00		RING2_HUMAN (2-188): 4.61e-29: 113: 18.72
+	Hs
		414669 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (9-186): 3.02e-28: 113: 17.22
+	Hs
		413131 P53_HUMAN (1-393): 0: 619: 100.00		RAG1_HUMAN (8-147): 1.25e-26: 110: 19.31
+	Hs
		414565 P53_HUMAN (1-393): 0: 619: 100.00		TRI31_HUMAN (6-156): 2.44e-25: 104: 17.65
+	Hs
		413688 P53_HUMAN (1-393): 0: 619: 100.00		RING1_HUMAN (2-74): 3.96e-21: 92.7: 27.40