HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RN125 (Q96EQ8)
E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)
Gene: RNF125

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	25591766
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0008270 - zinc ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 232
+	Hs
		413727 P53_HUMAN (1-393): 0: 619: 100.00		TRI26_HUMAN (22-228): 3.11e-46: 162: 14.88
+	Hs
		413166 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (22-227): 8.35e-42: 149: 13.30
+	Hs
		414669 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (28-229): 1.05e-38: 141: 16.90
+	Hs
		414565 P53_HUMAN (1-393): 0: 619: 100.00		TRI31_HUMAN (22-215): 2.91e-36: 133: 12.56
+	Hs
		414567 P53_HUMAN (1-393): 0: 619: 100.00		TRIM2_HUMAN (17-227): 8.94e-34: 130: 13.97
+	Hs
		414295 P53_HUMAN (1-393): 0: 619: 100.00		RN138_HUMAN (21-223): 2.32e-34: 125: 26.14
+	Hs
		413111 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (22-228): 2.61e-32: 124: 15.49
+	Hs
		414915 P53_HUMAN (1-393): 0: 619: 100.00		TRAF6_HUMAN (6-175): 1.76e-26: 108: 21.39
+	Hs
		413131 P53_HUMAN (1-393): 0: 619: 100.00		RAG1_HUMAN (26-140): 2.73e-25: 105: 27.73
+	Hs
		414263 P53_HUMAN (1-393): 0: 619: 100.00		LNX1_HUMAN (28-142): 9.69e-24: 101: 24.17