HitPredict

Interactor 1: H2A1B (P04908)
Histone H2A type 1-B/E (Histone H2A.2) (Histone H2A/a) (Histone H2A/m)
Gene: H2AC4

Interactor 2: MCM6 (Q14566)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM)
Gene: MCM6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27248496, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 821
+	Hs
		755958 H2A2A_HUMAN (1-130): 3.71e-68: 203: 96.92		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		418856 H2A1B_HUMAN (1-130): 5.44e-68: 202: 100.00		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		502253 H2A1_HUMAN (1-130): 4.52e-68: 202: 98.46		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		634003 H2A1D_HUMAN (1-130): 4.88e-68: 202: 99.23		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		755970 H2A3_HUMAN (1-130): 4.18e-68: 202: 99.23		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		755998 H2A1C_HUMAN (1-130): 3.83e-68: 202: 98.46		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		756016 H2A1H_HUMAN (1-128): 2.08e-67: 201: 98.44		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		756032 H2A1J_HUMAN (1-128): 1.72e-67: 201: 97.66		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		756020 H2A1A_HUMAN (1-130): 3.79e-67: 200: 92.37		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		418857 H2A1B_HUMAN (1-130): 5.44e-68: 202: 100.00		MCM7_HUMAN (22-713): 0: 634: 28.88
+	Hs
		755734 H2A2A_HUMAN (1-130): 3.71e-68: 203: 96.92		MCM4_HUMAN (2-736): 0: 632: 27.70
+	Hs
		418855 H2A1B_HUMAN (1-130): 5.44e-68: 202: 100.00		MCM4_HUMAN (2-736): 0: 632: 27.70
+	Hs
		888128 H2A2A_HUMAN (1-130): 3.71e-68: 203: 96.92		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		418885 H2A1B_HUMAN (1-130): 5.44e-68: 202: 100.00		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		502271 H2A1_HUMAN (1-130): 4.52e-68: 202: 98.46		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		634008 H2A1D_HUMAN (1-130): 4.88e-68: 202: 99.23		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		888153 H2A3_HUMAN (1-130): 4.18e-68: 202: 99.23		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		888231 H2A1C_HUMAN (1-130): 3.83e-68: 202: 98.46		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		888257 H2A1H_HUMAN (1-128): 2.08e-67: 201: 98.44		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Hs
		888282 H2A1J_HUMAN (1-128): 1.72e-67: 201: 97.66		MCM2_HUMAN (22-732): 0: 628: 28.40