HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: TFPT (P0C1Z6)
TCF3 fusion partner (INO80 complex subunit F) (Protein FB1)
Gene: TFPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.755

Property	Details
Experiments	25416956, 16189514, 25910212, 27107012, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, barcode fusion genetics two hybrid, split luciferase complementation, two hybrid bait and prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005884 - actin filament
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 253
+	Hs
		433110 LAMB1_HUMAN (7-281): 2.34e-53: 188: 21.56		TFPT_HUMAN (1-253): 3.83e-158: 440: 100.00
+	Hs
		451179 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		TFPT_HUMAN (1-253): 3.83e-158: 440: 100.00
+	Hs
		434330 TPM2_HUMAN (2-285): 1.42e-39: 141: 86.27		TFPT_HUMAN (1-253): 3.83e-158: 440: 100.00
+	Hs
		471606 Q5VU62_HUMAN (128-285): 1.66e-39: 137: 100.00		TFPT_HUMAN (1-253): 3.83e-158: 440: 100.00