HitPredict

Interactor 1: H2A2 (P04912)
Histone H2A.2
Gene: HTA2

Interactor 2: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.867

Property	Details
Experiments	19106085, 37968396, 20595233, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 132 Sc			1 914
+	Sc
		419482 H2A1_YEAST (1-132): 2.36e-62: 188: 98.49		ORC1_YEAST (1-914): 0: 798: 100.00
+	Sc
		419544 H2A2_YEAST (1-132): 1.11e-62: 189: 100.00		SIR3_YEAST (1-914): 0: 587: 26.50
+	Sc
		419319 H2A1_YEAST (1-132): 2.36e-62: 188: 98.49		SIR3_YEAST (1-914): 0: 587: 26.50
+	Hs
		1104313 H2A2C_HUMAN (3-130): 9.22e-63: 189: 73.44		ORC1_HUMAN (155-908): 9.82e-118: 381: 21.21
+	Sc
		419834 H2A2_YEAST (1-132): 1.11e-62: 189: 100.00		ORC4_YEAST (385-711): 1.7e-45: 174: 13.51
+	Hs
		935073 H2AJ_HUMAN (3-130): 3.29e-63: 190: 73.44		TERA_HUMAN (420-667): 3.73e-25: 114: 10.00
+	Hs
		591555 H2AX_HUMAN (3-125): 1.04e-61: 187: 76.42		TERA_HUMAN (420-667): 3.73e-25: 114: 10.00
+	Hs
		418863 H2A1B_HUMAN (3-128): 1.35e-62: 189: 74.60		RFC1_HUMAN (147-633): 9.82e-20: 97.4: 12.66