HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: TNNT1 (P13805)
Troponin T, slow skeletal muscle (TnTs) (Slow skeletal muscle troponin T) (sTnT)
Gene: TNNT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	25416956, 25910212
Identification Methods	two hybrid, two hybrid bait and prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Tropomyosin~Troponin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 278
+	Hs
		451185 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		TNNT1_HUMAN (1-278): 1.79e-90: 271: 100.00
+	Hs
		533602 Q5VU62_HUMAN (128-285): 1.66e-39: 137: 100.00		TNNT1_HUMAN (1-278): 1.79e-90: 271: 100.00
+	Hs
		451212 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		TNNT2_HUMAN (36-278): 1.37e-60: 195: 62.60