HitPredict

Interactor 1: CALCA (P06881)
Calcitonin gene-related peptide 1 (Alpha-type CGRP) (Calcitonin gene-related peptide I) (CGRP-I)
Gene: CALCA

Interactor 2: CALRL (Q16602)
Calcitonin gene-related peptide type 1 receptor (CGRP type 1 receptor) (Calcitonin receptor-like receptor)
Gene: CALCRL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 9620797, 23597562
Identification Methods biochemical, scintillation proximity assay
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_2~Calc_CGRP_IAPP, Calc_CGRP_IAPP~HRM
Common GO terms GO:0005737 - cytoplasm
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0031623 - receptor internalization
GO:1990408 - calcitonin gene-related peptide receptor signaling pathway
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 128
Hs

1 461
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024