HitPredict

Interactor 1: CAN1 (P07384)
Calpain-1 catalytic subunit (EC 3.4.22.52) (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP)
Gene: CAPN1

Interactor 2: AINX (Q16352)
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)
Gene: INA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 714 Hs			1 499
+	Hs
		422324 CAN1_HUMAN (1-714): 0: 950: 100.00		NFM_HUMAN (9-480): 1.71e-96: 313: 47.43
+	Hs
		427831 CAN1_HUMAN (1-714): 0: 950: 100.00		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		1081727 CAN12_HUMAN (23-714): 0: 724: 41.56		AINX_HUMAN (1-499): 1.25e-175: 504: 100.00
+	Hs
		427839 CAN1_HUMAN (1-714): 0: 950: 100.00		DESM_HUMAN (57-418): 4.71e-85: 271: 51.38
+	Hs
		422330 CALM3_HUMAN (532-617): 5.54e-14: 71.6: 20.69		NFM_HUMAN (9-480): 1.71e-96: 313: 47.43
+	Hs
		443283 CALM3_HUMAN (532-617): 5.54e-14: 71.6: 20.69		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91