HitPredict

Interactor 1: CDC4 (P07834)
Cell division control protein 4 (E3 ubiquitin ligase complex SCF subunit CDC4) (F-box protein CDC4)
Gene: CDC4

Interactor 2: CG11 (P20437)
G1/S-specific cyclin CLN1
Gene: CLN1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22844257
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 779 Sc			1 546
+	Sc
		431117 CDC4_YEAST (1-779): 0: 553: 100.00		CG12_YEAST (4-521): 2.73e-134: 402: 57.33
+	Sc
		431113 CDC4_YEAST (1-779): 0: 553: 100.00		CG13_YEAST (2-437): 1.4e-71: 241: 16.78
+	Sc
		431120 CDC4_YEAST (1-779): 0: 553: 100.00		CG23_YEAST (14-213): 2.36e-59: 204: 18.41
+	Hs
		624603 FBXW7_HUMAN (449-777): 4.6e-67: 237: 21.18		CCNE1_HUMAN (40-401): 7.56e-76: 247: 11.17
+	Hs
		331644 FBXW7_HUMAN (449-777): 4.6e-67: 237: 21.18		CCNE2_HUMAN (39-399): 3.5e-71: 235: 11.78
+	Hs
		779311 TBL3_HUMAN (393-777): 1.41e-47: 183: 13.90		CCNF_HUMAN (60-541): 3.16e-78: 263: 12.76
+	Hs
		780316 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNF_HUMAN (60-541): 3.16e-78: 263: 12.76
+	Hs
		943810 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNA1_HUMAN (3-301): 1.72e-77: 253: 15.26
+	Hs
		538625 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNB1_HUMAN (21-274): 1.21e-76: 250: 14.06
+	Hs
		624618 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNE1_HUMAN (40-401): 7.56e-76: 247: 11.17
+	Hs
		780349 FBW1A_HUMAN (603-777): 1.43e-28: 123: 13.89		CCNF_HUMAN (60-541): 3.16e-78: 263: 12.76
+	Mm
		624393 FZR1_MOUSE (385-668): 1.96e-34: 139: 14.42		CCNB1_MOUSE (21-274): 2.19e-75: 246: 13.67
+	Hs
		779152 WDR5_HUMAN (603-775): 6.17e-29: 120: 19.89		CCNF_HUMAN (60-541): 3.16e-78: 263: 12.76
+	Hs
		780297 FBW1B_HUMAN (603-777): 4.82e-27: 118: 13.89		CCNF_HUMAN (60-541): 3.16e-78: 263: 12.76
+	Mm
		851189 FZR1_MOUSE (385-668): 1.96e-34: 139: 14.42		CCNA2_MOUSE (15-295): 2.16e-71: 236: 13.99
+	Hs
		538630 FBW1A_HUMAN (603-777): 1.43e-28: 123: 13.89		CCNB1_HUMAN (21-274): 1.21e-76: 250: 14.06
+	Hs
		624620 FBW1A_HUMAN (603-777): 1.43e-28: 123: 13.89		CCNE1_HUMAN (40-401): 7.56e-76: 247: 11.17
+	Hs
		779896 SNR40_HUMAN (615-767): 2.99e-21: 98.2: 17.39		CCNF_HUMAN (60-541): 3.16e-78: 263: 12.76
+	Dm
		872375 FBXW7_DROME (664-777): 1.63e-17: 89.7: 11.30		CCNE_DROME (39-444): 1.2e-79: 265: 16.44
+	Hs
		590235 FZR1_HUMAN (385-680): 3.82e-35: 142: 14.50		CCNA2_HUMAN (25-204): 1.61e-54: 191: 19.44