Protein: PKHM1
Pleckstrin homology domain-containing family M member 1 (PH domain-containing family M member 1) (162 kDa adapter protein) (AP162)

Gene: PKHM1, PLEKHM1
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9Y4G2

Gene Ontology (top 5):
GO:0005730 - nucleolus
GO:0005764 - lysosome
GO:0015031 - protein transport
GO:0031902 - late endosome membrane
GO:0032418 - lysosome localization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

845381

RAB7A
Ras-related protein Rab-7a

5

20

Small-scale

0.926

High

833175

VPS41
Vacuolar protein sorting-associated protein 41 homolog

3

4

Small-scale

0.681

High

1350055

VPS18
Vacuolar protein sorting-associated protein 18 homolog

2

3

Small-scale

0.639

High

1346696

ARL8B
ADP-ribosylation factor-like protein 8B

2

8

Small-scale

0.631

High

1072672

RHEB
GTP-binding protein Rheb

1

10

Small-scale

0.618

High

306367

GBRAP
Gamma-aminobutyric acid receptor-associated protein

2

8

Small-scale

0.611

High

527909

LAMP2
Lysosome-associated membrane glycoprotein 2

2

10

Small-scale

0.611

High

1152222

LTOR1
Ragulator complex protein LAMTOR1

2

8

Small-scale

0.611

High

1284684

VP33A
Vacuolar protein sorting-associated protein 33A

2

1

Small-scale

0.611

High

1329152

VPS11
Vacuolar protein sorting-associated protein 11 homolog

2

3

Small-scale

0.611

High

787611

MTOR
Serine/threonine-protein kinase mTOR

1

3

Small-scale

0.586

High

897976

RAP1B
Ras-related protein Rap-1b

1

7

Small-scale

0.553

High

1326701

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

1

High-throughput

0.541

High

178885

STX7
Syntaxin-7

1

3

Small-scale

0.536

High

507332

LAMP1
Lysosome-associated membrane glycoprotein 1

1

10

Small-scale

0.536

High

878268

SEC13
Protein SEC13 homolog

1

3

Small-scale

0.536

High

1139784

RRAGB
Ras-related GTP-binding protein B

1

1

Small-scale

0.536

High

1162316

WDR59
GATOR2 complex protein WDR59

1

3

Small-scale

0.536

High

1184620

RRAGA
Ras-related GTP-binding protein A

1

1

Small-scale

0.536

High

1230075

RPTOR
Regulatory-associated protein of mTOR

1

6

Small-scale

0.536

High

1289608

SEH1
Nucleoporin SEH1

1

3

Small-scale

0.536

High

1295100

VPS39
Vam6/Vps39-like protein

1

4

Small-scale

0.536

High

1347916

MIOS
GATOR2 complex protein MIOS

1

1

Small-scale

0.536

High

588973

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

0

High-throughput

0.518

High

1377581

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.518

High

835135

TSC2
Tuberin

1

0

Small-scale

0.513

High

850610

VAMP7
Vesicle-associated membrane protein 7

1

0

Small-scale

0.513

High

1329140

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

Small-scale

0.513

High

1354605

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

0

Small-scale

0.513

High

1377346

LTOR2
Ragulator complex protein LAMTOR2

1

0

Small-scale

0.513

High

1317497

TRI54
Tripartite motif-containing protein 54

1

6

High-throughput

0.494

High

1313725

LST8
Target of rapamycin complex subunit LST8

1

1

Small-scale

0.489

High

1326229

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

8

Small-scale

0.481

High

1169036

DEFI8
Differentially expressed in FDCP 8 homolog

1

4

Small-scale

0.479

High

1326044

NDEL1
Nuclear distribution protein nudE-like 1

1

5

Small-scale

0.479

High

1085563

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.464

High

1241283

FA98A
Protein FAM98A

1

0

Small-scale

0.458

High

1348165

NSMA2
Sphingomyelin phosphodiesterase 3

1

0

High-throughput

0.438

High

1314348

KIFC1
Kinesin-like protein KIFC1

1

2

Small-scale

0.437

High

1298572

RILP
Rab-interacting lysosomal protein

1

0

Small-scale

0.426

High

839548

SPB9
Serpin B9

1

0

High-throughput

0.282

High

1067894

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.282

High

1021898

NPRL3
GATOR1 complex protein NPRL3

1

0

Small-scale

0.279

Low

1154447

PRR5L
Proline-rich protein 5-like

1

0

Small-scale

0.279

Low

1163921

RICTR
Rapamycin-insensitive companion of mTOR

1

0

Small-scale

0.279

Low

1308739

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

Small-scale

0.279

Low

1357525

STX8
Syntaxin-8

1

0

Small-scale

0.279

Low

309890

GA45G
Growth arrest and DNA damage-inducible protein GADD45 gamma

1

0

High-throughput

0.265

Low

879565

BID
BH3-interacting domain death agonist

1

0

High-throughput

0.265

Low

659098

MK01
Mitogen-activated protein kinase 1

1

0

Small-scale

0.261

Low

201482

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

Small-scale

0.249

Low

1357082

TPX2
Targeting protein for Xklp2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024