Protein: IFIT5
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58)

Gene: IFIT5
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q13325

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0000339 - RNA cap binding
GO:0003690 - double-stranded DNA binding
GO:0003723 - RNA binding
GO:0003727 - single-stranded RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

488176

IFIT1
Antiviral innate immune response effector IFIT1

2

17

High-throughput

0.806

High

166782

IFIT3
Interferon-induced protein with tetratricopeptide repeats 3

2

13

High-throughput

0.793

High

1102506

RNF41
E3 ubiquitin-protein ligase NRDP1

4

10

Small-scale

0.691

High

855865

CRKL
Crk-like protein

3

6

High-throughput

0.662

High

547439

DMD
Dystrophin

2

2

High-throughput

0.628

High

1102494

KCTD6
BTB/POZ domain-containing protein KCTD6

2

4

High-throughput

0.628

High

1102483

RBMS2
RNA-binding motif, single-stranded-interacting protein 2

2

15

High-throughput

0.601

High

1102480

CUL3
Cullin-3

1

7

High-throughput

0.575

High

1102504

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

4

High-throughput

0.575

High

1102507

LN28A
Protein lin-28 homolog A

2

7

High-throughput

0.571

High

177861

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

4

Small-scale

0.561

High

1102515

NEMO
NF-kappa-B essential modulator

1

2

Small-scale

0.561

High

1006375

SRPK2
SRSF protein kinase 2

1

4

High-throughput

0.550

High

1102499

SRPK1
SRSF protein kinase 1

1

3

High-throughput

0.550

High

732304

PRDX2
Peroxiredoxin-2

1

1

High-throughput

0.541

High

786085

LONM
Lon protease homolog, mitochondrial

1

5

High-throughput

0.541

High

923589

TTC3
E3 ubiquitin-protein ligase TTC3

1

12

High-throughput

0.541

High

931510

RD23A
UV excision repair protein RAD23 homolog A

1

4

High-throughput

0.541

High

1102484

CDC37
Hsp90 co-chaperone Cdc37

1

2

High-throughput

0.541

High

1102500

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

2

High-throughput

0.541

High

1102502

RNF32
RING finger protein 32

1

1

High-throughput

0.541

High

1102514

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

2

High-throughput

0.541

High

286972

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

9

High-throughput

0.536

High

431116

LA
Lupus La protein

1

18

High-throughput

0.536

High

686134

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.536

High

1102495

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

3

High-throughput

0.536

High

369672

A2MG
Alpha-2-macroglobulin

1

1

High-throughput

0.494

High

387417

APOE
Apolipoprotein E

1

1

High-throughput

0.481

High

890728

PSN2
Presenilin-2

1

1

High-throughput

0.481

High

167887

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

5

Small-scale

0.479

High

241585

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

247308

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

3

High-throughput

0.479

High

363224

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

425484

ISG15
Ubiquitin-like protein ISG15

1

11

High-throughput

0.479

High

467255

MDR1
ATP-dependent translocase ABCB1

1

2

High-throughput

0.479

High

558098

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

638166

MDR3
Phosphatidylcholine translocator ABCB4

1

2

High-throughput

0.479

High

642845

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.479

High

810077

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.479

High

879047

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

Small-scale

0.479

High

958940

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

4

High-throughput

0.479

High

1102482

EEA1
Early endosome antigen 1

1

4

High-throughput

0.479

High

1102485

ABCB5
ATP-binding cassette sub-family B member 5

1

2

High-throughput

0.479

High

1102486

LARP7
La-related protein 7

1

19

High-throughput

0.479

High

1102501

RIOK1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

1102503

ATG5
Autophagy protein 5

1

3

High-throughput

0.479

High

1102505

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.479

High

213922

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

Small-scale

0.458

High

273186

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

2

High-throughput

0.445

High

617295

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

2

High-throughput

0.445

High

713772

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

16

High-throughput

0.445

High

1016418

SRSF3
Serine/arginine-rich splicing factor 3

1

16

High-throughput

0.445

High

1102481

RHG19
Rho GTPase-activating protein 19

1

5

High-throughput

0.445

High

1102488

RBMS3
RNA-binding motif, single-stranded-interacting protein 3

1

15

High-throughput

0.445

High

1102490

TM10C
tRNA methyltransferase 10 homolog C

1

1

High-throughput

0.445

High

1102492

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.445

High

1102508

TNR6C
Trinucleotide repeat-containing gene 6C protein

1

5

High-throughput

0.445

High

1102513

AGO1
Protein argonaute-1

1

3

High-throughput

0.445

High

588609

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

695366

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

768102

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

1102489

TRI67
Tripartite motif-containing protein 67

1

14

High-throughput

0.437

High

1102491

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.437

High

1102510

ABCB9
ABC-type oligopeptide transporter ABCB9

1

4

High-throughput

0.437

High

1102511

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.437

High

1102512

XPO7
Exportin-7

1

9

High-throughput

0.437

High

388404

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

1102493

DI3L2
DIS3-like exonuclease 2

1

0

High-throughput

0.426

High

1102498

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.426

High

1102509

S40A1
Ferroportin

1

0

High-throughput

0.426

High

1102496

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

1

High-throughput

0.407

High

1102497

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.238

Low

1102487

FAXC
Failed axon connections homolog

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025