HitPredict

Interactor 1: SRC (P05480)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: NMDE2 (Q01097)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B)
Gene: Grin2b

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	18384166, 10862698
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005770 - late endosome GO:0005856 - cytoskeleton GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 535 Mm			1 1482
+	Rn
		1028070 SRC_RAT (1-535): 0: 641: 99.44		NMDE2_RAT (1-1482): 0: 1852: 99.46
+	Hs
		557276 SRC_HUMAN (1-535): 0: 640: 98.69		NMDE2_HUMAN (1-1482): 0: 1835: 98.38
+	Mm
		813511 FYN_MOUSE (1-535): 0: 593: 68.52		NMDE2_MOUSE (1-1482): 0: 1854: 100.00
+	Hs
		440532 FYN_HUMAN (1-535): 0: 594: 68.70		NMDE2_HUMAN (1-1482): 0: 1835: 98.38
+	Mm
		431328 SRC_MOUSE (1-535): 0: 648: 100.00		NMDE1_MOUSE (9-1482): 0: 1512: 52.84
+	Rn
		1028059 SRC_RAT (1-535): 0: 641: 99.44		NMDE1_RAT (9-1482): 0: 1503: 52.58
+	Hs
		557262 SRC_HUMAN (1-535): 0: 640: 98.69		NMDE1_HUMAN (9-1482): 0: 1495: 52.38
+	Mm
		771409 FYN_MOUSE (1-535): 0: 593: 68.52		NMDE1_MOUSE (9-1482): 0: 1512: 52.84
+	Hs
		440518 FYN_HUMAN (1-535): 0: 594: 68.70		NMDE1_HUMAN (9-1482): 0: 1495: 52.38
+	Mm
		431329 SRC_MOUSE (1-535): 0: 648: 100.00		NMDZ1_MOUSE (14-940): 0: 676: 23.44
+	Rn
		771530 SRC_RAT (1-535): 0: 641: 99.44		NMDZ1_RAT (14-940): 0: 678: 23.54
+	Hs
		440504 FYN_HUMAN (1-535): 0: 594: 68.70		NMDZ1_HUMAN (14-940): 0: 673: 23.54