HitPredict

Interactor 1: TNR16 (P08138)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: NGFR

Interactor 2: TNR16 (P08138)
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)
Gene: NGFR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 27084575, 14960584, 11756426
Identification Methods affinity chromatography technology, pull down, cross-linking study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, TNFR_16_TM~TNFR_16_TM, TNFR_c6~TNFR_c6
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001678 - intracellular glucose homeostasis
GO:0004888 - transmembrane signaling receptor activity
GO:0005035 - death receptor activity
GO:0005516 - calmodulin binding
and 46 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 427
Hs

1 427
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Last updated: 15 Jul 2024