Interactor 1: UBC2 (P06104)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)
Gene: RAD6
Interactor 2: UBR1 (P19812)
E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27) (N-end-recognizing protein) (N-recognin-1)
Gene: UBR1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.986 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10581257, 8505328, 19164530, 8436296, 12391316, 12535539, 37968396, 36162503, 7926769, 10850718, 1651502, 28515311, 34789879, 39920309, 21076411, 21179020 |
| Identification Methods | affinity chromatography technology, two hybrid, coimmunoprecipitation, pull down, enzymatic study, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UBR1-like_wing~UQ_con |
| Common GO terms | GO:0000209 - protein polyubiquitination GO:0004842 - ubiquitin-protein transferase activity GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0034620 - cellular response to unfolded protein and 6 others more... |
| Homologous interactions | 14 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
