Protein: UBC2
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Radiation sensitivity protein 6) (Ubiquitin carrier protein UBC2) (Ubiquitin-protein ligase UBC2)

Gene: UBC2, RAD6
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P06104

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0000785 - chromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438516

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

21

20

Small-scale

0.991

High

438550

BRE1
E3 ubiquitin-protein ligase BRE1

18

20

Small-scale

0.990

High

438519

UBR1
E3 ubiquitin-protein ligase UBR1

16

14

Small-scale

0.986

High

438551

UBR2
E3 ubiquitin-protein ligase UBR2

9

13

Small-scale

0.972

High

438521

UBA1
Ubiquitin-activating enzyme E1 1

7

20

Small-scale

0.959

High

380913

H2B1
Histone H2B.1

5

8

Small-scale

0.931

High

381352

H2B2
Histone H2B.2

3

8

Small-scale

0.845

High

438513

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

2

20

Small-scale

0.778

High

438511

UBC2
Ubiquitin-conjugating enzyme E2 2

2

15

Small-scale

0.737

High

438531

SWD2
COMPASS component SWD2

1

4

Small-scale

0.647

High

438535

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

19

Small-scale

0.647

High

438542

RTF1
RNA polymerase-associated protein RTF1

3

2

Small-scale

0.646

High

438545

MUB1
MYND-type zinc finger protein MUB1

4

0

Small-scale

0.644

High

438518

PCNA
Proliferating cell nuclear antigen

1

4

Small-scale

0.621

High

438541

UBC9
SUMO-conjugating enzyme UBC9

1

15

Small-scale

0.621

High

438532

PAF1
RNA polymerase II-associated protein 1

2

1

Small-scale

0.595

High

401806

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

4

Small-scale

0.584

High

438537

BRE2
COMPASS component BRE2

1

1

Small-scale

0.515

High

438522

BUR1
Serine/threonine-protein kinase BUR1

1

4

Small-scale

0.501

High

438533

LEO1
RNA polymerase-associated protein LEO1

1

3

Small-scale

0.501

High

438543

CTR9
RNA polymerase-associated protein CTR9

1

3

Small-scale

0.501

High

438549

CDC73
Cell division control protein 73

1

3

Small-scale

0.501

High

438540

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.493

High

438548

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.493

High

395210

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.480

High

438520

PSB4
Proteasome subunit beta type-4

1

8

Small-scale

0.479

High

438524

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

438525

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

438539

CUL8
Cullin-8

1

17

Small-scale

0.479

High

438512

F16P
Fructose-1,6-bisphosphatase

1

0

Small-scale

0.458

High

438514

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

438515

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

438517

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

438523

CDC48
Cell division control protein 48

1

1

High-throughput

0.445

High

438526

PSB5
Proteasome subunit beta type-5

1

6

Small-scale

0.445

High

438534

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.445

High

438536

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.445

High

438528

BMH2
Protein BMH2

1

0

High-throughput

0.426

High

438529

CENPC
Inner kinetochore subunit MIF2

1

0

High-throughput

0.426

High

438538

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

438544

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

438546

SND1
SRP-independent targeting protein 1

1

0

High-throughput

0.426

High

438547

POLH
DNA polymerase eta

1

2

Small-scale

0.408

High

438527

EMP24
Endosomal protein P24B

1

0

High-throughput

0.238

Low

438530

YKP3
Putative uncharacterized protein YKL153W

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025