Protein: UBR2
E3 ubiquitin-protein ligase UBR2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase UBR2) (Ubiquitin-protein ligase E3 component N-recognin-1 homolog)

Gene: UBR2
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: Q07963

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

438551

UBC2
Ubiquitin-conjugating enzyme E2 2

9

13

Small-scale

0.972

High

1042831

RPN4
Protein RPN4

4

0

Small-scale

0.671

High

826887

DSN1
Kinetochore-associated protein DSN1

5

1

Small-scale

0.651

High

1041490

MUB1
MYND-type zinc finger protein MUB1

2

0

Small-scale

0.598

High

805444

BZZ1
Protein BZZ1

1

0

High-throughput

0.518

High

580165

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.493

High

1061330

DET1
Broad-range acid phosphatase DET1

1

0

High-throughput

0.493

High

708358

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

748079

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

367534

TRPF
N-(5'-phosphoribosyl)anthranilate isomerase

1

0

High-throughput

0.458

High

394951

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.458

High

704662

SBA1
Co-chaperone protein SBA1

1

0

High-throughput

0.458

High

803171

ECM29
Proteasome component ECM29

1

0

High-throughput

0.458

High

805912

YHU0
UPF0641 membrane protein YHR140W

1

0

High-throughput

0.458

High

814095

MTW1
Kinetochore-associated protein MTW1

1

0

Small-scale

0.458

High

851026

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.458

High

924369

MDG1
Signal transduction protein MDG1

1

0

High-throughput

0.458

High

925340

SIW14
Inositol diphosphatase SIW14

1

0

High-throughput

0.458

High

1031063

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

1038423

YP067
Uncharacterized protein YPL067C

1

0

High-throughput

0.458

High

1044274

FIN1
Filament protein FIN1

1

0

Small-scale

0.458

High

1061329

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

525341

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

527837

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

546510

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

742963

HSP79
Heat shock protein homolog SSE2

1

4

High-throughput

0.445

High

660518

HXT2
High-affinity glucose transporter HXT2

1

1

High-throughput

0.437

High

802053

HXT5
Probable glucose transporter HXT5

1

1

High-throughput

0.437

High

824880

NDC80
Kinetochore protein NDC80

1

2

Small-scale

0.437

High

917739

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

1

Small-scale

0.437

High

1038114

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.437

High

804507

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

1047292

ERB1
Ribosome biogenesis protein ERB1

1

0

High-throughput

0.279

Low

700158

PRP45
Pre-mRNA-processing protein 45

1

0

Small-scale

0.251

Low

624815

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.249

Low

755308

NUF2
Kinetochore protein NUF2

1

0

Small-scale

0.249

Low

757548

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

High-throughput

0.249

Low

780514

MCR1
NADH-cytochrome b5 reductase 2

1

0

High-throughput

0.249

Low

807661

PET8
Putative mitochondrial carrier protein PET8

1

0

High-throughput

0.249

Low

817038

SPC25
Kinetochore protein SPC25

1

0

Small-scale

0.249

Low

830245

RMRP
Ribonuclease MRP protein subunit SNM1

1

0

High-throughput

0.249

Low

844380

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.249

Low

851258

SFT1
Protein transport protein SFT1

1

0

High-throughput

0.249

Low

923780

PRM1
Plasma membrane fusion protein PRM1

1

0

High-throughput

0.249

Low

1038169

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.249

Low

1044048

RIFK
Riboflavin kinase

1

0

High-throughput

0.249

Low

1046595

ZWINT
Outer kinetochore KNL1 complex subunit KRE28

1

0

Small-scale

0.249

Low

1046718

SPC24
Kinetochore protein SPC24

1

0

Small-scale

0.249

Low

1059774

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.249

Low

1061328

NSL1
Kinetochore-associated protein NSL1

1

0

Small-scale

0.249

Low

626903

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025