Interactor 1: RPB2 (P08518)
DNA-directed RNA polymerase II subunit RPB2 (RNA polymerase II subunit 2) (EC 2.7.7.6) (B150) (DNA-directed RNA polymerase II 140 kDa polypeptide)
Gene: RPB2

Interactor 2: SPT5 (P27692)
Transcription elongation factor SPT5 (Chromatin elongation factor SPT5)
Gene: SPT5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.960

The method score is based on:

Property Details
Experiments 23209026, 12556496, 16085932, 16554755, 37968396, 21467036, 24813444
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_1~Spt5-NGN, KOW~RNA_pol_Rpb2_6, KOW~RNA_pol_Rpb2_7
Common GO terms GO:0003677 - DNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0006368 - transcription elongation by RNA polymerase II
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1224
Sc

1 1063
+ Hs
+ Hs
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+ Pf

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Last updated: 15 Jul 2024