HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: Q58EY0 (Q58EY0)
RAR related orphan receptor B isoform 1 (RAR-related orphan receptor B) (cDNA, FLJ93970, Homo sapiens RAR-related orphan receptor B (RORB), mRNA)
Gene: RORB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 459
+	Hs
		440164 LCK_HUMAN (1-509): 0: 655: 100.00		RORB_HUMAN (2-459): 7.3e-137: 403: 99.78
+	Hs
		557182 SRC_HUMAN (20-507): 0: 585: 55.00		RORG_HUMAN (2-454): 9.81e-106: 325: 46.25
+	Hs
		463404 LYN_HUMAN (1-509): 0: 581: 62.72		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		440536 FYN_HUMAN (1-507): 0: 587: 54.19		STF1_HUMAN (3-447): 7.16e-82: 262: 21.55
+	Hs
		557279 SRC_HUMAN (20-507): 0: 585: 55.00		STF1_HUMAN (3-447): 7.16e-82: 262: 21.55
+	Hs
		543451 SRC_HUMAN (20-507): 0: 585: 55.00		VDR_HUMAN (3-453): 6.67e-82: 261: 21.44
+	Hs
		282918 FGR_HUMAN (1-507): 0: 579: 52.76		NR1I2_HUMAN (8-452): 8.21e-81: 258: 22.72
+	Hs
		879001 BTK_HUMAN (3-505): 4.99e-166: 486: 33.40		NR2C2_HUMAN (1-447): 1.02e-99: 312: 18.75
+	Hs
		362275 ABL1_HUMAN (34-502): 6.9e-173: 518: 41.09		STF1_HUMAN (3-447): 7.16e-82: 262: 21.55
+	Hs
		520501 SRC_HUMAN (20-507): 0: 585: 55.00		RARA_HUMAN (9-84): 3.94e-43: 159: 61.84
+	Hs
		557079 SRC_HUMAN (20-507): 0: 585: 55.00		RXRA_HUMAN (10-91): 4.43e-28: 117: 57.32
+	Mm
		362437 ABL1_MOUSE (34-502): 4.64e-173: 519: 41.09		PPARG_MOUSE (8-128): 7.57e-46: 167: 46.34